Richard Ebright has recieved the Searle Scholar Award and
the Schering Plough Award for Biochemistry and Molecular Biology. It was his
fascination for butterflies that opened the world of science to him.
READ AND FIND OUT
• How did a book become a turning point in Richard Ebright’s
life?
• How did his mother help him?
AT the age of twenty-two, a former ‘scout of the year’
excited the scientific world with a new theory on how cells work. Richard H.
Ebright and his college room-mate explained the theory in an article in the
Proceedings of the National Academy of Science.
It was the first time this important scientific journal had
ever published the work of college students. In sports, that would be like
making the big leagues at the age of fifteen and hitting a home run your first
time at bat*. For Richard Ebright, it was the first in a long string of
achievements in science and other fields. And it all started with butterflies.
An only child, Ebright grew up north of
So he did, and did he ever! Beginning in kindergarten,
Ebright collected butterflies with the same determination that has marked all
his activities. He also collected rocks, fossils, and coins. He became an eager
astronomer, too, sometimes star-gazing all night.
* A home run in the game of baseball is when the batter
scores a run after running safely around all bases and back to the home plate
without stopping. A ball hit out of the playing field is also called a home
run. Getting a paper published at the age of fifteen in a scientific journal is
here compared to scoring a home run while batting for the first time.
From the first he had a driving curiosity along with a
bright mind. He also had a mother who encouraged his interest in learning. She
took him on trips, bought him telescopes, microscopes, cameras, mounting
materials, and other equipment and helped him in many other ways.
“I was his only companion until he started school,” his
mother said. “After that I would bring home friends for him. But at night we
just did things together. Richie was my whole life after his father died when
Richie was in third grade.”
She and her son spent almost every evening at the dining
room table. “If he didn’t have things to do, I found work for him — not
physical work, but learning things,” his mother said. “He liked it. He wanted
to learn.”
And learn he did. He earned top grades in school. “On
everyday things he was just like every other kid,” his mother said.
By the time he was in the second grade, Ebright had collected all twentyfive species of butterflies found around his hometown. (See following box.)
Species
and Sub-species of Butterflies Collected in Six
Weeks in Reading, Pennsylvania |
||
Gossamer-Winged
Butterflies •
white M hairstreak •
acadian hairstreak •
bronze copper •
bog copper •
purplish copper •
eastern-tailed blue •
melissa blue •
silvery blue Snout
Butterfly |
Wood
Nymphs and Satyrs •
eyed brown •
wood nymph (grayling) Monarchs •
monarch or milkweed Whites
and Sulphurs •
olympia •
cloudless sulphur •
European cabbage |
Brush-footed
Butterflies •
variegated fritillary •
Harris’s checkerspot •
pearl crescent •
mourning cloak •
painted lady •
buckeye •
viceroy •
white admiral •
red-spotted purple • hackberry |
“That probably would
have been the end of my butterfly collecting,” he said. “But then my mother got
me a children’s book called The Travels of Monarch X.” That book, which told
how monarch butterflies migrate to
At the end of the book, readers were invited to help study
butterfly migrations. They were asked to tag butterflies for research by Dr
Frederick A. Urquhart of the University of Toronto, Canada. Ebright’s mother
wrote to Dr Urquhart, and soon Ebright was attaching light adhesive tags to the
wings of monarchs. Anyone who found a tagged butterfly was asked to send the
tag to Dr Urquhart.
The butterfly collecting season around
“Eventually I began to lose interest in tagging butterflies. It’s tedious and there’s not much feedback,” Ebright said. “In all the time I did it,” he laughed, “only two butterflies I had tagged were recaptured — and they were not more than seventy-five miles from where I lived.”
THE MAKING OF A NEW SCIENTIST (C)
READ AND FIND OUT
• What lesson does Ebright learn when he does not win
anything at a science fair?
• What experiments and projects does he then undertake?
• What are the qualities that go into the making of a
scientist?
Then in the seventh grade he got a hint of what real science
is when he entered a county science fair — and lost. “It was really a sad
feeling to sit there and not get anything while everybody else had won
something,” Ebright said. His entry was slides of frog tissues, which he showed
under a microscope. He realised the winners had tried to do real experiments,
not simply make a neat display.
Already the competitive spirit that drives Richard Ebright
was appearing. “I knew that for the next year’s fair I would have to do a real
experiment,” he said. “The subject I knew most about was the insect work I’d
been doing in the past several years.”
So he wrote to Dr Urquhart for ideas, and back came a stack
of suggestions for experiments. Those kept Ebright busy all through high school
and led to prize projects in county and international science fairs.
For his eighth grade project, Ebright tried to find the
cause of a viral disease that kills nearly all monarch caterpillars every few
years. Ebright thought the disease might be carried by a beetle. He tried
raising caterpillars in the presence of beetles. “I didn’t get any real
results,” he said. “But I went ahead and showed that I had tried the
experiment. This time I won.”
The next year his science fair
project was testing the theory that viceroy butterflies copy monarchs. The
theory was that viceroys look like monarchs because monarchs don’t taste good
to birds. Viceroys, on the other hand, do taste good to birds. So the more they
look like monarchs, the less likely they are to become a bird’s dinner.
Ebright’s project was to see whether, in fact, birds would
eat monarchs. He found that a starling would not eat ordinary bird food. It
would eat all the monarchs it could get. (Ebright said later research by other
people showed that viceroys probably do copy the monarch.) This project was placed first in the zoology division and
third overall in the county science fair. How is the monarch butterfly (top)
different from the viceroy butterfly (bottom)?
In his second year in
high school, Richard Ebright began the research that led to his discovery of an
unknown insect hormone. lndirectly, it also led to his new theory on the life
of cells. The question he tried to answer was simple: What is the purpose of
the twelve tiny gold spots on a monarch pupa?
“Everyone assumed the spots were just ornamental,” Ebright
said.
“
To find the answer, Ebright and another excellent science
student first had to build a device that showed that the spots were producing a
hormone necessary for the butterfly’s full development.
This project won Ebright first place in the county fair and
entry into the International Science and Engineering Fair. There he won third
place for zoology. He also got a chance to work during the summer at the
entomology laboratory of the Walter Reed Army Institute of Research.
As a high school junior, Richard Ebright continued his
advanced experiments on the monarch pupa. That year his project won first place
at the International Science Fair and gave him another chance to work in the
army laboratory during the summer.
In his senior year, he went a step further. He grew cells
from a monarch’s wing in a culture and showed that the cells would divide and
develop into normal butterfly wing scales only if they were fed the hormone
from the gold spots. That project won first place for zoology at the
International Fair. He spent the summer after graduation doing further work at
the army laboratory and at the laboratory of the U.S. Department of
Agriculture.
The following summer, after his freshman year at Harvard
University, Ebright went back to the laboratory of the Department of
Agriculture and did more work on the hormone from the gold spots. Using the
laboratory’s sophisticated instruments, he was able to identify the hormone’s
chemical structure.
A year-and-a-half later, during his junior year, Ebright got
the idea for his new theory about cell life. It came while he was looking at
X-ray photos of the chemical structure of a hormone.
When he saw those photos, Ebright didn’t shout, ‘Eureka!’ or
even, ‘I’ve got it!’ But he believed that, along with his findings about insect
hormones, the photos gave him the answer to one of biology’s puzzles: how the
cell can ‘read’ the blueprint of its DNA. DNA is the substance in the nucleus
of a cell that controls heredity. It determines the form and function of the
cell. Thus DNA is the blueprint for life.
Ebright and his college room-mate, James R. Wong, worked all
that night drawing pictures and constructing plastic models of molecules to
show how it could happen. Together they later wrote the paper that explained
the theory.
Surprising no one who knew him, Richard Ebright graduated
from Harvard with highest honours, second in his class of 1,510. Ebright went
on to become a graduate student researcher at
If the theory proves correct, it will be a big step towards
understanding the processes of life. It might also lead to new ideas for
preventing some types of cancer and other diseases. All of this is possible
because of Ebright’s scientific curiosity. His high school research into the
purpose of the spots on a monarch pupa eventually led him to his theory about
cell life.
Richard Ebright has been interested in science since he
first began collecting butterflies — but not so deeply that he hasn’t time for
other interests. Ebright also became a champion debater and public speaker and
a good canoeist and all-around outdoors-person. He is also an expert
photographer, particularly of nature and scientific exhibits. In high school
Richard Ebright was a straight-A student. Because learning was easy, he turned
a lot of his energy towards the Debating and Model United Nations clubs. He
also found someone to admire —
Richard A. Weiherer, his social studies teacher and adviser
to both clubs. “Mr Weiherer was the perfect person for me then. He opened my
mind to new ideas,” Ebright said.
“Richard would always give that extra effort,” Mr Weiherer
said. “What pleased me was, here was this person who put in three or four hours
at night doing debate research besides doing all his research with butterflies
and his other interests.
“Richard was competitive,” Mr Weiherer continued, “but not
in a bad sense.” He explained, “Richard wasn’t interested in winning for
winning’s sake or winning to get a prize. Rather, he was winning because he
wanted to do the best job he could. For the right reasons, he wants to be the
best.”
And that is one of the ingredients in the making of a
scientist. Start with a first-rate mind, add curiosity, and mix in the will to
win for the right reasons. Ebright has these qualities. From the time the book,
The Travels of Monarch X, opened the world of science to him, Richard Ebright
has never lost his scientific curiosity.
ROBERT W. PETERSON
GLOSSARY
Leagues:
groups of sports clubs or teams playing matches among themselves
County:
region
Starling:
common European bird (with black, brown-spotted plumage) which nests near
buildings and is a good mimic
Entomology:
the study of insects
Eureka:
a cry of triumph at a discovery (originally attributed to Archimedes)
Canoeist:
a person who paddles a canoe, a light boat
Think
about it
1.
How can one become a scientist, an economist, a historian... ? Does it simply
involve reading many books on the subject? Does it involve observing, thinking
and doing experiments?
2.
You must have read about cells and DNA in your science books. Discuss Richard
Ebright’s work in the light of what you have studied. If you get an opportunity
to work like Richard Ebright on projects and experiments, which field would you
like to work on and why?
Talk
about it
1.
Children everywhere wonder about the world around them. The questions they ask
are the beginning of scientific inquiry. Given below are some questions that
children in India have asked Professor Yash Pal and Dr Rahul Pal as reported in
their book,
Discovered
Questions (NCERT, 2006).
(i) What is DNA fingerprinting? What are its uses?
(ii) How do honeybees identify their own honeycombs?
(iii) Why does rain fall in drops?
Can
you answer these questions? You will find Professor Yash Pal’s and Dr Rahul
Pal’s answers (as given in Discovered Questions) on page 75.
2.
You also must have wondered about certain things around you. Share these
questions with your class, and try and answer them.
Suggested reading
•
‘Journey by Night’ by Norah Burke
•
Children Who Made It Big by Thangamani
•
School Days by Tom Brown
1.
Children everywhere wonder about the world around them. The questions they ask
are the beginning of scientific inquiry. Given below are some questions that
children in India have asked Professor Yash Pal and Dr Rahul Pal as reported in
their book,
Discovered
Questions (NCERT, 2006).
(i) What is DNA fingerprinting? What are its uses?
(ii) How do honeybees identify their own honeycombs?
(iii) Why does rain fall in drops?
Can
you answer these questions? You will find Professor Yash Pal’s and Dr Rahul Pal’s
answers (as given in Discovered Questions) on page 75.
Answers
given by Professor Yash Pal and Dr Rahul Pal
(see
questions on page 38)
(i) DNA exists as strands of bases that carry genetic
information specific to each living thing. The sequence of bases of DNA in each
of our cells is the same, but differs from that of any other living thing
except possibly an identical twin. This difference makes the DNA break at
different places when certain proteins called enzymes are added to it,
resulting in smaller DNA fragments of different sizes. These fragments migrate
at different rates in an electric field, resulting in a unique pattern; this
pattern is referred to as a DNA fingerprint.
Our DNA is inherited from our parents. Some parts come from
the father and some from the mother. DNA fingerprinting can help identify
parentage, since a son or a daughter would always exhibit a pattern
identifiable as coming from both parents. DNA fingerprinting analysis is very
useful in forensic science; from a single hair or a tiny spot of blood, it is
possible to prove the innocence or guilt of a murder suspect. Similarly, it is
also possible to identify human remains after violent accidents have caused
disfigurement.
It has been suggested that in the not so distant future, a
DNA fingerprinting profile of the individual will have to accompany
applications for an ID card, a bank account and a driving license. Human right
groups say this type of “genetic profiling” constitutes an invasion of privacy.
As with a lot of new technology, DNA fingerprinting also has a potential for
abuse.
(ii) Honeybees are very sophisticated at position location and navigation. It is known that they use the sun as a guide. They also appear to have a good memory. They convey the information of a new find of food to the hive through an amazingly clever dance language. The dance indicates the direction and distance of the food source with respect to the direction of the sun in the sky! If it is dark inside the hive and a light bulb is switched on, the dance is modified to include the light bulb as a new reference direction!
Since
bees have pictorial memory of some sort, a direction-finding mechanism and a
way of reckoning distance, they are probably better equipped for getting back
home than any of us!
(iii) Rain is the result of condensation of vapour when the
air is cooled below the dew point. All the vapour in a cloud cannot condense at
the same time and turn into a large pool of water. Pockets of air move up
independently and slowly cool till condensation begins and water droplets form.
It is believed that most raindrops start out as tiny ice crystals — so tiny
that they float down, slowly accreting more moisture on the way; at lower
altitudes, the crystals melt into water droplets. In colder climates, the
crystals reach the ground as snowflakes.
Post a Comment
Post a Comment